English summaries Suom Lääkäril 2023; 78 : e33271 www.laakarilehti.fi/e33271 (Julkaistu 30.1.2023)

Liver transplantation patients have a good long-term prognosis in the Hospital District of Southwest Finland

Tapio NevalaEliisa LöyttyniemiMarkku VoutilainenKimmo Salminen

Background In view of the improved short-term outcomes in liver transplantation patients, more research has been done on the long-term sequelae in this patient group. The progression of chronic diseases can be prevented with optimal immunosuppressive medications and regular follow-up appointments.

Methods In this study, data was gathered from liver transplantation patients from the year 2000 onwards in the Hospital District of Southwest Finland (VSSHP). In this patient group short- and long-term outcomes and survival were analysed.

Results Liver transplantation patients (n = 89) have a favourable prognosis in VSSHP. Survival was 100%, 93% and 86%, at 1, 5 and 10 years, respectively. The cumulative incidence for cancer was 0%, 7%, 11% and 39% at 1, 5, 10 and 20 years, respectively. Kidney function had deteriorated one year after the surgery, but no statistically significant deterioration was observed at 5 years. At 5 years, hypertension had developed in 56% of cases, dyslipidaemia in 18% and diabetes in 7%.

Conclusions According to the study, liver transplantation patients have encouraging long-term outcomes in Southwest Finland. The weakness of the study was that not all relevant information was available from the department of liver surgery of Helsinki University Hospital.

Tapio Nevala, Eliisa Löyttyniemi, Markku Voutilainen, Kimmo Salminen

Tapio Nevala

Lic. Med.

Turku University Hospital, Department of Gastroenterology, and University of Turku

Kirjoittajat

Tapio Nevala lääketieteen lisensiaatti

Eliisa Löyttyniemi tilastotieteilijä, biostatistiikka Turun yliopisto

Markku Voutilainen professori emeritus Turun yliopisto

Kimmo Salminen erikoislääkäri, lääketieteen tohtori Tyks, gastroenterologian vastuualue ja Turun yliopisto

Lääkäriliitto Fimnet Lääkärilehti Potilaanlaakarilehti Lääkäripäivät Lääkärikompassi Erikoisalani Lääkäri 2030